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Seattle Seahawks vs San Francisco 49ers: odds and preview

StartSunday, October 11, 2026 at 8:25 PM UTC
CompetitionNFL · American football

Our odds

Match winner
Seattle Seahawks1.52
San Francisco 49ers2.42
Point spread
Seattle Seahawks (-3.5)1.85
San Francisco 49ers (+3.5)1.89

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Preview

On October 11, Seattle Seahawks take on San Francisco 49ers in NFL. Seattle Seahawks hold a slight edge in our numbers: 61% against 39% for San Francisco 49ers.

Seattle Seahawks, recent form: W L W W W (4-1 in wins and defeats). San Francisco 49ers, recent form: W W W W L (4-1 in wins and defeats). Head-to-head record in our data (Seattle Seahawks wins, San Francisco 49ers wins): 2-1. Last meeting: Seattle Seahawks 41-6 San Francisco 49ers, on January 18, 2026.

For San Francisco 49ers, an upset here would be a statement result; Seattle Seahawks have more to lose than to gain. Prices can move until the start, so lock in the one you like.

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